𝙋𝙨𝙮𝙘𝙝𝙤𝙨𝙞𝙨 𝙖𝙣𝙙 𝙎𝙘𝙝𝙞𝙯𝙤𝙥𝙝𝙧𝙚𝙣𝙞𝙖 𝙞𝙣 𝙃𝙤𝙣𝙜 𝙆𝙤𝙣𝙜 covers some of the most serious mental health conditions that top the global disease burden and affect 3 per cent of the general population. However, most research on psychotic disorders is undertaken in the West, and few studies have been systematically carried out in Asia despite global interest in regional differences. This work offers a unique and coherent account of these disorders and their treatment in Hong Kong over the last thirty years.

Chen and his research programme’s pioneering work has ranged from the impact of early intervention on outcomes and relapse prevention, to the renaming of psychosis to reduce stigma. The studies have contributed to wider international debates on the optimal management of the condition. Their investigations in semantics and cognition, as well as cognition-enhancing exercise interventions, have provided novel insights into deficits encountered in psychotic disorders and how they might be ameliorated. The research has also explored subjective experiences of psychosis and elicited unique perspectives in patients of Asian origin.

Each topic is divided into three sections: a global background of the challenges encountered; research findings from Hong Kong; and reflections that place the data in scientific and clinical contexts and offer future directions.